Left behind: the potential impact of CFTR modulators on racial and ethnic disparities in cystic fibrosis
ME McGarry, ER Gibb, GR Oates… - Paediatric respiratory …, 2022 - Elsevier
The advent of CFTR modulators, a genomic specific medication, revolutionized the treatment
of CF for many patients. However, given that these therapeutics were only developed for
specific CFTR mutations, not all people with CF have access to such disease-modifying
drugs. Racial and ethnic minority groups are less likely to have CFTR mutations that are
approved for CFTR modulators. This exclusion has the potential to widen existing health
disparities.
of CF for many patients. However, given that these therapeutics were only developed for
specific CFTR mutations, not all people with CF have access to such disease-modifying
drugs. Racial and ethnic minority groups are less likely to have CFTR mutations that are
approved for CFTR modulators. This exclusion has the potential to widen existing health
disparities.
